Recurrent Giant Sarcoma of the Anterior Abdominal Wall

Sarcomas are a heterogeneous group of malignant neoplasms arising from mesenchymal cells. They account for less than 1% of adult solid malignant cancers. The vast majority are soft tissue sarcomas, while malignant bone tumors represent only about 10% of them [1]. In fact, sarcomas comprise over 50 different histological subtypes; they may arise in stem cell-like population (primitive neuroectodermal tumors) as well as from morphologically recognizable connective tissues [2]. Although the tumorigenesis of sarcoma is not well understood, the risk factors can be divided into environmental exposures, genetic susceptibility and an interaction between the two [1]. Considerable evidence supports a relationship between occupational chemicals, medicinal treatment, such as Thorotrast exposure, therapeutic irradiation and the development of soft tissue sarcoma [3].